Thanks to the new revolutionary application on HB&L and Alfred 60, positive blood cultures can be tested with Alifax Antibiotic Susceptibility Test kits, thus dramatically reducing the analytical turnaround time.
Results are available within 3 hours from the analysis start.
Comparing to traditional methods Alifax AST results about antibiotics effectiveness are available from 24 to 48 hours sooner.
Sample preparation is very easy and required few minutes. The method is applicable to the positive hemoculture obtained with the most diffused hemoculture bottle.
3 scientific works were produced in 2010: 2 scientific papers published in the Microbiologia Medica national journal and 1 poster presented at the European Society of Intensive Care Medicine (ESICM) Annual Congress 2010.
The conclusions of the publications are: The HB&L® (ALIFAX) is rapid reliable instrument able to offer significant benefits to the clinician thanks to the speed with which it provides sensitivity or resistance data, while maintaining reproducibility performances, similar to the most popular test on the market. (Kroumova et al. Mic Med 2010)
The timing of reporting (4-5 hours), far below the traditional methods, allow to obtain stronger performance especially on sepsis. In this way, we can get quick results, saving at least 24 hours (the time required for the performance of traditional methods) and providing clinical antibiotic-resistance data in less time (Barocci et al. Mic Med 2010)
This new application, at the moment for research use only, will be soon CE marked.
1- V. Kroumova et al. (Microbiology and Virology laboratory from university mayor hospital of charity of Novara, Italy) “Preliminary
indications for antibiotic susceptibility tests in less than six hour in positive blood cultures” Microbiologia Medica, Anno 2010, Vol. 25,
N° 1, 24-26
2- S. Barocci et al. (Microbiology Unit, Clinical Pathology Laboratories ASUR 4 Senigallia (AN), Italy) “HB&L System: rapid determination of antibiotic sensitivity of bacteria isolated from blood cultures” Microbiologia Medica, Anno 2010, Vol. 25, N° 1, 60-63